PRODUCTS

CellO-IF & CellO-M

High-Resolution In Situ Imaging
of Organoids, Spheroids, and Cells

Explore [GALLERIES] for real-world lab examples

CellO-IF: The Smarter Way to Label

CellO-IF is an all-in-one reagent

that makes immunofluorescence labeling studies easy, simple, and more accurate.

It eliminates harmful workflow steps that cause loss and damage of delicate samples, allowing you to label the entire sample in its growing habitat. This provides more data with better accuracy.

Broad compatibility:

It is fully compatible with various hydrogels and glass-bottom cell culture plates.

Simplified workflow:

You only need your primary and secondary antibodies plus CellO-IF for the experiment.

In Situ Precision:

You can label the entire sample while it remains in its native microenvironment

(even within hydrogels),

resulting in highly specific labeling

without the need for manual specimen transfer.

Tailored for your 2D/3D cell culture models:

CellO-IF2

All-in-one-reagent for

immunofluorescence labeling

of 2D Cell Culture Models

Protocol & Product Information Sheet

CellO-IF3

All-in-one-reagent for

immunofluorescence labeling

of 3D Cell Culture Models:

Organoids

Spheroids

Organ-on-Chip Models

Protocol & Product Information Sheet

Learn More

CellO-M: The Smarter Way to Microscopy

It is all-in-one platform

for streamlined workflows for 2D/3D cell culture and microscopic analysis. It simplifies protocols and ensures optimal sample preservation for high-quality data.

CellO-M provides a controlled, biocompatible environment for the complete cycle of 2D/3D cell cultures; including growing, cryopreservation, labeling, and imaging .

You can culture organoids, spheroids or cells, freeze/thaw, and then label, stain and coat them for analysis, and finally image them under a light, confocal or electron microscope

– all within a single, sterile platform.

CellO-M

Learn More

'CellO-IF and CellO-M can be used together or separately.'

GALLERY 1:

CellO - IF2 in Action

Immunofluorescent Labeling of Cells

Primary Astrocytes

GALLERY 2:
CellO - IF3 in Action:

Immunofluorescent Labeling of Organoids and Spheroids

®

GALLERY 3:

CellO-M in Action

Effortless Workflow + High-Quality Data

Culture and analyze your organoids, spheroids, or cells under any microscope—light, confocal, or electron—in a single, contamination-free environment

Liver Cancer Spheroids Grown in CellO-M

SEM visualization of a liver cancer spheroid and its surrounding microenvironment within the CellO-M platform.

Dorsal Root Ganglion Cell

This TEM image reveals the ultrastructural feature of a Dorsal Root Ganglion cell following an integrated in situ workflow. The cells were cultivated, processed, and embedded in resin entirely within a CellO-M, ensuring the stabilization of delicate neuronal structures. Following resin polymerization, the blocks were sectioned and stained to allow for the precise visualization of internal organelles and membrane integrity at nanometer-scale resolution.

HepG2 Cells Under SEM

This SEM image demonstrates the growth and stabilization of HepG2 cells on a collagen-coated surface within a CellO-M. By performing the entire sequence—from initial cultivation and fixation to processing and coating—directly within the device, the native cellular morphology and fine structural attachments remain undisturbed. This integrated approach provides a high-fidelity representation of liver cancer cell topography and its interaction with the extracellular matrix.

Mitochondrion

This high-magnification TEM image captures the precise spatial organization of a mitochondrion situated between the granular endoplasmic reticulum and the nucleus. Located within a 3D spheroid, these organelles exhibit pristine ultrastructural detail, serving as a testament to the success of the CellO-M integrated workflow. By performing all stages—from initial cultivation to final resin block preparation—entirely within the device, the delicate internal architecture of the cell is preserved with high fidelity.

New Products

*Patent Pending Technologies

CellO - T*

A multipurpose cell culture container for your delicate samples from the start of growth until transplantation

Coming Soon

CellO - S*

A uniquely designed cell culture container for boosting spheroid formation, for drug design and drug screening experiments

Coming Soon

CellO - P*

®

A game changer to enhance immunohistochemical staining on your paraffin sections. Get your results within same day. A smart consumable for pathology laboratories

Contact Us to Order

CellO - F*

®

DMSO-free freezing medium for organoids and spheroids. It is designed to freeze samples while they are still in the gel.